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BrandsDoctor's Formulas D-Mannose Dietary Supplement For Maintaining Urinary System Health 60 Capsules
Doctor's Formulas D-Mannose Dietary Supplement For Maintaining Urinary System Health 60 Capsules
Formula D - Mannose is a dietary supplement containing the monosaccharide D-mannose.
D-mannose helps to support and maintain the health of the urinary system, because it attaches to lectins and thus prevents the attachment of pathogens to the walls of the bladder.
What is D-Mannose?
D-mannose is a simple sugar, which has a special contribution to metabolism, through its role in the glycosylation of certain proteins. D-mannose is rapidly absorbed and reaches the peripheral organs in about 30 minutes and is then excreted by the urinary system. It cannot be converted to glycogen, therefore it is not stored in the body.
Action mechanism :
Its mechanism of action is expressed by inhibiting the adhesion of E. coli to uroepithelial cells via the FimH surface protein. By direct binding of FimH to D-mannose bound to a vector protein, which is responsible for receptor specificity. In vitro studies have identified the specific lectin for mannose on the surface of E. coli adherent strains. D-mannose occupies a dominant position in the receptors of bladder cells, in terms of E. coli uropathogen.
The first adhesion step involves the binding of mannose-sensitive FimH to the bladder epithelium. The bladder wall is coated with various mannose-glycosylated proteins, such as Tamm-Horsfall protein (THP), which directly interferes with the adhesion of germs to the mucosa. Tamm-Horsfall protein (THF) can bind to E. coli with a specific bond, which can be inhibited by exogenous D-mannose.
By inhibiting the adhesion of germs to the urinary tract epithelium, D-mannose mimics the function of the urinary tract epithelial barrier.
The process of microbial adhesion to the cell surface is a critical factor in the occurrence of most infections. This is because specific lectins in the microbial wall are capable of binding molecules, such as D-mannose and L-fucose, that are distributed on the human cell surface. to cling to.
EOF Notification Number: 47421 / 27-04-2018
(The Notification Number to the EOF is not a marketing authorization from the EOF)
COMPOSITION IN NUTRITIONS | PER DAILY INSTALLMENT (1 to 2 capsules) |
|---|---|
D - Mannose | 500 - 1000 mg |
OTHER INGREDIENTS: magnesium stearate, gelatin, silicon dioxide.
(*) Does not contain preservatives, gluten, perfumes, sweeteners, etc.
WARNINGS:
• Do not exceed the recommended daily dose.
S / D should not be used as a substitute for a balanced diet.
• Keep out of the reach of small children.
• This product is not intended to prevent, treat or cure any human disease.
• Ask your doctor if you are pregnant, breast-feeding, taking medication or have any health problems.
Contents: 60 capsules
Dosage: 1 to 2 capsules per day
